Cell Culture

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In Situ Mammalian Cell Culture Analysis for R&D and Mass Production

For use in analyzing both R&D and mass production of Mammalian Cell based biopharmaceutical products. On-line monitoring of Cell Culture reaction provides fast results and can be incorporated into the process control system. 

The Need for analysis In-Situ of the Cell Culture reaction process:

The Mammalian Cell Culture process varies greatly with organisms behaving differently and metabolizing at varying rates. With in-process measurements you can monitor the key parameters and optimize the Cell Culture process.

LT-NIR Analysis of Cell Culture properties:

·        Glucose

·        Lactate

·        Dry Cell Weight

·        Glutamine

·        Optical Density

·        Ammonia

·        Titer

·        and more

Using the IsoPharm Cell Culture analyzer allows for analysis of many different properties with one quick measurement.  With so many different media in use for Mammalian Cell Culture biopharmaceuticals, your needs might be different than those shown.  Contact us with your specific needs and we would be glad to discuss an online or laboratory measurement solution with you.

 

Mammalian Cell Culture processes in a closed vessel can benefit greatly from in-process or in situ chemical analysis.  Large-scale fermenters can hold as many as 250,000 gallons of raw material, which may be in process for hours or several weeks.  The IsoPharm Cell Culture Analyzer can monitor both the raw materials and emerging product on-line, despite the thick, soupy nature of the material. 

Online Cell Culture measurements of Glucose, Ammonia, and much more with the Cell Culture Analyzer.  These properties and more can be measured In-Situ or in the lab and using LT Industries optical multiplexer, one analyzer can monitor many fermenters, sending all the valuable data to your process control system automatically. 

In mass production the electrical power savings alone can provide payback for an NIR analyzer within a few months.  Added product yield from improved process control can generate enormous payback, as well as reducing the occurrences of lost batches.

Paying too much for your laboratory analysis of Cell Culture properties?  The IsoPharm Cell Culture analyzer provides a very low cost per measurement for many properties as well as analysis of other products.  The analyzers are easy to use and provides results in seconds.  Sounds too good to be true?  Contact us  and let us show you the benefits our Cell Culture measurement solutions can bring.

 

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